Ectopic macroprolactinoma mimicking a chordoma: a case report.

نویسندگان

D Ballaux

J Verhelst

B Pickut

P P De Deyn

C Mahler

چکیده

A tumoral mass at the clivus is uncommon and its differential diagnosis presents a challenge, since many different tumours may result in a similar radiological image. A chordoma is the most common of these tumours and represents 40% of all cases. Less common, in decreasing order of frequency, are meningiomas, astrocytoma, germinal cell tumours, lymphoma, metastases and, finally, pituitary adenoma (Wong et al. 1995). The last type of tumour is rarely found in this localisation and is called an ectopic pituitary adenoma, as almost all pituitary adenomas are detected in the sella turcica, where they originate from, and in the immediate suprasellar and parasellar region. Outside of these sites, pituitary adenomas can be detected as a result of extensive invasion of nearby structures, metastasis of a pituitary carcinoma, or an ectopic localisation. The majority of these ectopic primary adenomas are situated outside the blood-brain barrier and mostly in the sphenoid sinus (Tovi et al. 1990). An intact pituitary gland supports the diagnosis of ectopic pituitary tumour, although cases of ectopic pituitary tumour have been reported with involvement of the intrasellar pituitary. In this article, we present an unusual intracranial ectopic pituitary adenoma located in the clivus and mimicking a chordoma.

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